Eric L Nuermberger Selected Research

Pyrazinamide

1/2022	Novel Regimens of Bedaquiline-Pyrazinamide Combined with Moxifloxacin, Rifabutin, Delamanid and/or OPC-167832 in Murine Tuberculosis Models.
1/2021	Comparative Efficacy of the Novel Diarylquinoline TBAJ-587 and Bedaquiline against a Resistant Rv0678 Mutant in a Mouse Model of Tuberculosis.
1/2019	Contribution of Pretomanid to Novel Regimens Containing Bedaquiline with either Linezolid or Moxifloxacin and Pyrazinamide in Murine Models of Tuberculosis.
1/2017	Bactericidal and Sterilizing Activity of a Novel Regimen with Bedaquiline, Pretomanid, Moxifloxacin, and Pyrazinamide in a Murine Model of Tuberculosis.
7/2015	Evaluation of moxifloxacin-containing regimens in pathologically distinct murine tuberculosis models.
3/2015	A novel inhibitor of gyrase B is a potent drug candidate for treatment of tuberculosis and nontuberculosis mycobacterial infections.
2/2015	Daily rifapentine for treatment of pulmonary tuberculosis. A randomized, dose-ranging trial.
8/2013	Potent rifamycin-sparing regimen cures guinea pig tuberculosis as rapidly as the standard regimen.
7/2013	Contribution of moxifloxacin or levofloxacin in second-line regimens with or without continuation of pyrazinamide in murine tuberculosis.
11/2012	Activity of 5-chloro-pyrazinamide in mice infected with Mycobacterium tuberculosis or Mycobacterium bovis.

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Eric L Nuermberger Research Topics

Disease

62	Tuberculosis (Tuberculoses) 01/2022 - 02/2004
29	Infections 01/2022 - 08/2009
16	Buruli Ulcer 01/2022 - 07/2010
12	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 01/2022 - 08/2009
7	Granuloma 04/2016 - 09/2004
6	Pulmonary Tuberculosis 01/2022 - 08/2009
4	Body Weight (Weight, Body) 01/2019 - 07/2012
3	Hypoxia (Hypoxemia) 01/2020 - 03/2009
3	Latent Tuberculosis 01/2017 - 12/2009
3	Necrosis 04/2016 - 06/2015
2	Acquired Immunodeficiency Syndrome (AIDS) 12/2021 - 06/2020
2	Lung Diseases (Lung Disease) 11/2021 - 01/2019
2	Ulcer 01/2019 - 01/2013
1	Communicable Diseases (Infectious Diseases) 01/2022
1	Extensively Drug-Resistant Tuberculosis 11/2021
1	Persistent Infection 01/2021
1	Bacterial Infections (Bacterial Infection) 12/2020
1	Cystic Fibrosis (Mucoviscidosis) 12/2020
1	Nontuberculous Mycobacterium Infections 01/2019
1	Hearing Loss (Hearing Impairment) 01/2015
1	Neglected Diseases 01/2014
1	Skin Diseases (Skin Disease) 10/2011
1	Cicatrix (Scar) 03/2011
1	HIV Infections (HIV Infection) 07/2010
1	Emerging Communicable Diseases (Emerging Infectious Diseases) 07/2010
1	Respiratory Insufficiency (Respiratory Failure) 11/2002
1	Sickle Cell Anemia (Hemoglobin S Disease) 11/2002
1	Sepsis (Septicemia) 11/2002

Drug/Important Bio-Agent (IBA)

40	Pharmaceutical PreparationsIBA 01/2022 - 09/2004
23	Rifampin (Rifampicin)FDA LinkGeneric 01/2022 - 02/2004
20	Isoniazid (Ftivazide)FDA LinkGeneric 01/2022 - 02/2004
20	Pyrazinamide FDA LinkGeneric 01/2022 - 02/2004
15	rifapentine (Priftin)FDA Link 01/2022 - 12/2005
14	Moxifloxacin (Avelox)FDA Link 01/2022 - 02/2004
13	AerosolsIBA 01/2019 - 03/2009
11	bedaquiline (R207910)IBA 01/2022 - 09/2011
11	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 04/2011
11	pretomanidIBA 11/2021 - 01/2011
10	RifamycinsIBA 01/2022 - 07/2006
7	Linezolid (Zyvox)FDA Link 11/2021 - 08/2009
6	FluoroquinolonesIBA 01/2022 - 04/2011
5	Streptomycin (Streptomycin Sulfate)FDA Link 01/2019 - 10/2010
5	Clofazimine (Lamprene)FDA Link 01/2019 - 05/2013
4	VaccinesIBA 01/2020 - 09/2011
4	Ethambutol (Myambutol)FDA LinkGeneric 07/2015 - 08/2012
3	Drug CombinationsIBA 01/2022 - 04/2011
3	LactamsIBA 01/2022 - 01/2019
3	DiarylquinolinesIBA 11/2021 - 01/2021
3	telacebecIBA 10/2021 - 01/2019
3	NitroimidazolesIBA 01/2020 - 01/2011
3	Oxazolidinones (2 Oxazolidone)IBA 01/2019 - 08/2009
2	OPC-67683IBA 01/2022 - 01/2020
2	Meropenem (Merrem)FDA LinkGeneric 01/2022 - 01/2022
2	Antitubercular AgentsIBA 01/2022 - 01/2020
2	Carbapenems (Carbapenem Antibiotics)IBA 01/2022 - 01/2021
2	Imipenem FDA Link 11/2021 - 01/2019
2	ProdrugsIBA 01/2020 - 03/2015
2	Oxidoreductases (Dehydrogenase)IBA 01/2020 - 01/2019
2	mycolactoneIBA 01/2019 - 01/2013
2	AcidsIBA 01/2014 - 10/2012
2	Biomarkers (Surrogate Marker)IBA 01/2012 - 01/2011
1	Clavulanic Acid (Potassium Clavulanate)FDA LinkGeneric 01/2022
1	Rifabutin (Ansamycin)FDA Link 01/2022
1	AcetyltransferasesIBA 12/2021
1	TBAJ-876IBA 11/2021
1	Vitamin K 2 (Vitamin K2)IBA 01/2020
1	Dihydrotachysterol (AT 10)IBA 01/2019
1	Lipoproteins (Lipoprotein)IBA 01/2019
1	Clarithromycin (Biaxin)FDA LinkGeneric 01/2019
1	MacrolidesIBA 01/2019
1	Tigecycline (Tygacil)FDA Link 01/2019
1	relebactamIBA 01/2019
1	meropenem and vaborbactamIBA 01/2019
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2016
1	Matrix Metalloproteinases (MMPs)IBA 01/2016
1	Oxygen (Dioxygen)IBA 03/2015
1	VXc-486IBA 03/2015
1	TBA-354IBA 01/2015
1	Levofloxacin (Levaquin)FDA Link 07/2013
1	beta-LactamsIBA 05/2013
1	trichostatin A (A 300)IBA 11/2012
1	Fatty Acids (Saturated Fatty Acids)IBA 10/2012
1	CarbonIBA 10/2012
1	NitrogenIBA 10/2012
1	pimonidazoleIBA 02/2012
1	7- (7- amino- 7- methyl- 5- azaspiro(2.4)heptan- 5- yl)- 6- fluoro- 1- (2- fluoro- 1- cyclopropyl)- 1,4- dihydro- 8- methoxy- 4- oxo- 3- quinolinecarboxylic acidIBA 04/2011
1	CytokinesIBA 03/2011
1	Glucose (Dextrose)FDA LinkGeneric 11/2009
1	PNU-100480IBA 08/2009
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2009
1	Dioctyl Sulfosuccinic Acid (DOSS)IBA 03/2009
1	Interferon-gamma (Interferon, gamma)IBA 09/2004

Therapy/Procedure

10	Duration of Therapy 01/2022 - 02/2004
7	Therapeutics 01/2019 - 11/2002
7	Drug Therapy (Chemotherapy) 01/2017 - 02/2004
3	Skin Transplantation (Skin Grafting) 01/2022 - 10/2011
2	Aftercare (After-Treatment) 01/2016 - 01/2013
2	Intramuscular Injections 01/2015 - 10/2010
1	Salvage Therapy 01/2019
1	Combination Drug Therapy (Combination Chemotherapy) 07/2010